E.g., flower or TO:0000303.
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Term Name | I-kappaB phosphorylation |
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Term Accession | GO:0007252 |
Aspect | biological_process |
Synonyms (4) | IkappaB phosphorylation, IKB phosphorylation, inhibitor of kappaB phosphorylation, inhibitor of NF-kappaB phosphorylation |
Definition | The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. |
Comment | None |
Source Ontology Database | The GO browser of Gene Ontology Database |
GOC: | jl |
GOC: | bf |
PMID: | 21772278 |
PMID: | 7594468 |