biological_process Term "gene silencing by miRNA" (GO:0035195)

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E.g., flower or TO:0000303.

E.g., d1 or waxy.

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biological_process Term "gene silencing by miRNA" (GO:0035195)

Term Name	gene silencing by miRNA
Term Accession	GO:0035195
Aspect	biological_process
Synonyms (3)	gene silencing by microRNA, microRNA-mediated gene silencing, miRNA-mediated gene silencing
Definition	Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
Comment	None
Source Ontology Database	The GO browser of Gene Ontology Database

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Derivation

biological_process (GO:0008150) #8951

[i] metabolic process (GO:0008152) #33238

[i] organic substance metabolic process (GO:0071704) #0

[i] macromolecule metabolic process (GO:0043170) #0

[i] gene expression (GO:0010467) #0

[r] regulation of gene expression (GO:0010468) #78

[i] posttranscriptional regulation of gene expression (GO:0010608) #15

[i] posttranscriptional gene silencing (GO:0016441) #62

[i] posttranscriptional gene silencing by RNA (GO:0035194) #167

[i] gene silencing by miRNA (GO:0035195) #273

[p] production of miRNAs involved in gene silencing by miRNA (GO:0035196) #141

[p] negative regulation of translation involved in gene silencing by miRNA (GO:0035278) #1

[p] mRNA cleavage involved in gene silencing by miRNA (GO:0035279) #261

[p] miRNA loading onto RISC involved in gene silencing by miRNA (GO:0035280) #247

[p] pre-miRNA export from nucleus (GO:0035281) #1

[r] regulation of gene silencing by miRNA (GO:0060964) #2

[-r] negative regulation of gene silencing by miRNA (GO:0060965) #0

[+r] positive regulation of gene silencing by miRNA (GO:2000637) #0

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Database Cross-References (3)

PMID:	15066275
PMID:	15066283
PMID:	14744438

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Parents (1)

posttranscriptional gene silencing by RNA (GO:0035194)

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Children (8)

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Associations (273)

Arabidopsis thaliana gene (4)

Brachypodium distachyon gene (4)

Brassica rapa gene (4)

Oryza sativa indica gene (5)

Oryza sativa japonica gene (5)

Sorghum bicolor gene (1)

Vitis vinifera gene (2)

Zea mays gene (2)

Gramene Gene (246)