cellular_component Term "proton-transporting two-sector ATPase complex" (GO:0016469)

Term Name	proton-transporting two-sector ATPase complex
Term Accession	GO:0016469
Aspect	cellular_component
Synonyms (2)	hydrogen-transporting two-sector ATPase complex, vacuolar hydrogen-transporting ATPase
Definition	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
Comment	None
Source Ontology Database	The GO browser of Gene Ontology Database