E.g., flower or TO:0000303.
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Term Name | G-protein coupled receptor signaling pathway |
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Term Accession | GO:0007186 |
Aspect | biological_process |
Synonyms (9) | G protein coupled receptor protein signaling pathway, G protein coupled receptor protein signalling pathway, G-protein coupled receptor protein signal transduction, G-protein coupled receptor protein signaling pathway, G-protein coupled receptor signalling pathway, G-protein-coupled receptor protein signaling pathway, G-protein-coupled receptor protein signalling pathway, GPCR signaling pathway, GPCR signalling pathway |
Definition | A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. |
Comment | None |
Source Ontology Database | The GO browser of Gene Ontology Database |
GOC: | mah |
GOC: | bf |
Wikipedia: | G_protein-coupled_receptor |