molecular_function Term "GDP-mannose 6-dehydrogenase activity" (GO:0047919)

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molecular_function Term "GDP-mannose 6-dehydrogenase activity" (GO:0047919)

Term Name	GDP-mannose 6-dehydrogenase activity
Term Accession	GO:0047919
Aspect	molecular_function
Synonyms (5)	GDP mannose dehydrogenase activity, GDP-D-mannose:NAD+ 6-oxidoreductase activity, GDPmannose 6-dehydrogenase activity, guanosine diphospho-D-mannose dehydrogenase activity, guanosine diphosphomannose dehydrogenase activity
Definition	Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH.
Comment	None
Source Ontology Database	The GO browser of Gene Ontology Database

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Derivation

molecular_function (GO:0003674) #8429

[i] catalytic activity (GO:0003824) #33842

[i] oxidoreductase activity (GO:0016491) #27384

[i] oxidoreductase activity, acting on CH-OH group of donors (GO:0016614) #1234

[i] oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616) #1943

[i] GDP-mannose 6-dehydrogenase activity (GO:0047919) #0

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Database Cross-References (6)

EC:	1.1.1.132
EC:	1.1.1.132
RHEA:	21731
RHEA:	21731
KEGG:	R00880
MetaCyc:	GDP-MANNOSE-6-DEHYDROGENASE-RXN

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Parents (1)

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

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