molecular_function Term "25-hydroxycholesterol 7alpha-hydroxylase activity" (GO:0033783)

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molecular_function Term "25-hydroxycholesterol 7alpha-hydroxylase activity" (GO:0033783)

Term Name	25-hydroxycholesterol 7alpha-hydroxylase activity
Term Accession	GO:0033783
Aspect	molecular_function
Synonyms (4)	25-hydroxycholesterol 7alpha-monooxygenase activity, cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase activity
Definition	Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.
Comment	None
Source Ontology Database	The GO browser of Gene Ontology Database

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Derivation

molecular_function (GO:0003674) #8429

[i] catalytic activity (GO:0003824) #33842

[i] oxidoreductase activity (GO:0016491) #27384

[i] monooxygenase activity (GO:0004497) #5935

[i] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709) #100

[i] 25-hydroxycholesterol 7alpha-hydroxylase activity (GO:0033783) #0

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Database Cross-References (4)

EC:	1.14.13.100
EC:	1.14.13.100
MetaCyc:	RXN-7980
MetaCyc:	RXN-7981

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Parents (1)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

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