molecular_function Term "aldehyde dehydrogenase (NAD) activity" (GO:0004029)

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molecular_function Term "aldehyde dehydrogenase (NAD) activity" (GO:0004029)

Term Name	aldehyde dehydrogenase (NAD) activity
Term Accession	GO:0004029
Aspect	molecular_function
Synonyms (9)	aldehyde dehydrogenase (NAD+), aldehyde:NAD+ oxidoreductase activity, CoA-independent aldehyde dehydrogenase activity, m-methylbenzaldehyde dehydrogenase activity, NAD-aldehyde dehydrogenase activity, NAD-dependent 4-hydroxynonenal dehydrogenase activity, NAD-dependent aldehyde dehydrogenase activity, NAD-linked aldehyde dehydrogenase activity, propionaldehyde dehydrogenase activity
Definition	Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
Comment	None
Source Ontology Database	The GO browser of Gene Ontology Database

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Derivation

molecular_function (GO:0003674) #8429

[i] catalytic activity (GO:0003824) #33842

[i] oxidoreductase activity (GO:0016491) #27384

[i] oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903) #1

[i] oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620) #727

[i] aldehyde dehydrogenase (NAD) activity (GO:0004029) #26

[i] betaine-aldehyde dehydrogenase activity (GO:0008802) #15

[i] lactaldehyde dehydrogenase activity (GO:0008911) #0

[i] phenylacetaldehyde dehydrogenase activity (GO:0008957) #0

[i] formaldehyde dehydrogenase activity (GO:0018467) #1

[i] 2-carboxybenzaldehyde dehydrogenase activity (GO:0018474) #0

[i] benzaldehyde dehydrogenase (NAD+) activity (GO:0018479) #27

[i] 4-hydroxybenzaldehyde dehydrogenase activity (GO:0018484) #0

[i] salicylaldehyde dehydrogenase activity (GO:0018485) #0

[i] aryl-aldehyde dehydrogenase (NAD) activity (GO:0019108) #0

[i] aminobutyraldehyde dehydrogenase activity (GO:0019145) #3

[i] fluoroacetaldehyde dehydrogenase activity (GO:0033723) #0

[i] 2-naphthaldehyde dehydrogenase activity (GO:0034520) #0

[i] 4-hydroxymethylsalicyaldehyde dehydrogenase activity (GO:0034530) #0

[i] 4-hydroxyphenylacetaldehyde dehydrogenase activity (GO:0047106) #0

[i] gamma-guanidinobutyraldehyde dehydrogenase activity (GO:0047107) #0

[i] 2-oxoaldehyde dehydrogenase (NAD) activity (GO:0047551) #0

[i] long-chain-aldehyde dehydrogenase activity (GO:0050061) #0

[i] glycolaldehyde dehydrogenase activity (GO:0050569) #0

[i] medium-chain-aldehyde dehydrogenase activity (GO:0052814) #0

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Database Cross-References (52)

EC:	1.2.1.3
EC:	1.2.1.3
MetaCyc:	ALDHDEHYDROG-RXN
Reactome:	REACT_100473
Reactome:	REACT_103621
Reactome:	REACT_104849
Reactome:	REACT_105050
Reactome:	REACT_105669
Reactome:	REACT_105847
Reactome:	REACT_105932
Reactome:	REACT_1080
Reactome:	REACT_110301
Reactome:	REACT_110943
Reactome:	REACT_112729
Reactome:	REACT_112808
Reactome:	REACT_113173
Reactome:	REACT_113214
Reactome:	REACT_113740
Reactome:	REACT_114032
Reactome:	REACT_114609
Reactome:	REACT_115403
Reactome:	REACT_15407
Reactome:	REACT_16919
Reactome:	REACT_2127
Reactome:	REACT_30242
Reactome:	REACT_30317
Reactome:	REACT_30455
Reactome:	REACT_31589
Reactome:	REACT_34252
Reactome:	REACT_78762
Reactome:	REACT_80267
Reactome:	REACT_81293
Reactome:	REACT_83193
Reactome:	REACT_83627
Reactome:	REACT_83939
Reactome:	REACT_84001
Reactome:	REACT_85596
Reactome:	REACT_86116
Reactome:	REACT_86294
Reactome:	REACT_86661
Reactome:	REACT_87336
Reactome:	REACT_88233
Reactome:	REACT_89302
Reactome:	REACT_89718
Reactome:	REACT_91587
Reactome:	REACT_91840
Reactome:	REACT_93677
Reactome:	REACT_97751
Reactome:	REACT_99086
RHEA:	16188
UM-BBD_enzymeID:	e0024
Wikipedia:	Aldehyde_dehydrogenase_(NAD+)

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Parents (1)

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620)

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Children (19)

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Associations (26)

Arabidopsis thaliana gene (7)

Brassica rapa gene (17)

Glycine max gene (1)

Zea mays gene (1)