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expand all sections collapse all sections  biological_process Term "RNA-directed DNA methylation" (GO:0080188)
Term Name RNA-directed DNA methylation
Term Accession GO:0080188
Aspect biological_process
Synonyms (1) RdDM
Definition An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci.
Comment None
Source Ontology Database The GO browser of Gene Ontology Database
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