Reference "A gene proposed to encode a transmembrane domain of an ABC transporter is expressed in wheat mitochondria"

Reference ID

9264

Title

A gene proposed to encode a transmembrane domain of an ABC transporter is expressed in wheat mitochondria

Source

Molecular & General Genetics, 1995, vol. 246, pp. 91-99

Authors (2)

Bonnard-G

Grienenberger-J-M

Abstract

In a study of transcribed regions of the wheat mitochondrial genome, we
identified an open reading frame of 720 bp, which was consequently designated
orf240. The amino acid sequence deduced from orf240 shows a high level of
similarity with HelC, a protein essential for c-type cytochrome biogenesis in
the photosynthetic purple bacterium Rhodobacter capsulatus. HelC is part of a
putative heme ABC transporter. An open reading frame homologous to orf240 is
present in the mitochondrial genome of Marchantia polymorpha. The wheat gene is
expressed as an mRNA of 2.8 kb, which is further processed to smaller
transcripts. The transcript is highly edited, with 36 C to U modifications found
in the coding region of all cDNAs sequenced. RNA editing is responsible for
changes in 14% of the amino acids specified by the transcript.