Reference "Mitochondrial genome rearrangement leads to extension and relocation of the cytochrome c oxidase subunit I gene in sorghum"

Reference ID

9019

Title

Mitochondrial genome rearrangement leads to extension and relocation of the cytochrome c oxidase subunit I gene in sorghum

Source

Cell, 1986, vol. 47, pp. 567-576

Authors (4)

Bailey-Serres-J	Hanson-D-K
Fox-T-D	Leaver-C-J

Abstract

The mitochondrial gene (COXI) encoding cytochrome c oxidase subunit I (COI) was
isolated from two cytoplasmic genotypes of sorghum that synthesize different COI
polypeptides. The Milo COI (Mr approximately 38,000) is encoded by a 530 codon
structural gene sharing 98% homology with the corresponding maize gene. A
variant COI observed in 9E cytoplasm (Mr approximately 42,000) is encoded by a
631 codon structural gene that diverges completely from the Milo COXI gene both
100 bp 5' to the presumed initiator methionine and within the 3' coding
sequence. The 3' divergence results in a 101 C-terminal extension of the 9E COI
that is not homologous to any known mitochondrial polypeptide. The novel 9E
COXI, apparently arising from at least two rearrangements, affects transcription
and gene product.