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expand all sections collapse all sections Zea mays subsp. mays gene "hm1" (GR:0200254)
Species Zea mays subsp. mays (Maize) [ GR_tax:014546 ]
Accession GR:0200254
Gene Symbol hm1
Gene Name Helminthosporium carbonum susceptibility1 
Synonyms (3)
E.C. Numbers (0)
Pathway Reactions (0)
Chromosome No. 1
Gene Type Not classified
Has Phenotype not curated
Description Disease lesions vs. yellowish flecks (Hm1, resistant) on leaves with Cochliobolus carbonum race 1. Dominant Hm1, resistance (yellow flecks) to Cochliobolus carbonum (=Bipolaris zeicola; Helminthosporium carbonum) race 1. In hm1/hm1 plants, severity of disease lesions is determined by the allelic state at the hm2 locus, but Hm1 alleles are epistatic to hm2 (Nelson and Ullstrip 1964 J Hered 55:194). There are also alleles (hm1-A and hm1-B) conditioning intermediate degrees of resistance in plants that are also hm2/hm2. (O. Nelson) Hm1 encodes for NADPH-dependent reductase whose function is to reduce (detoxify) the HC-toxin that the fungus produces to cause disease in susceptible maize. The locus has been cloned from B73 (Johal and Briggs 1992 Sci 258:985). This gene was originally curated in MaizeGDB Database and the map position was displayed on the maize bins map if feasible.
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toggle section Map Positions (3)
toggle section Gene Map Positions (3)
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toggle section Database Cross-References (1)
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