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expand all sections collapse all sections Oryza sativa gene "Dcl1" (GR:0101251)
Species Oryza sativa (Rice) [ GR_tax:013681 ]
Accession GR:0101251
Gene Symbol Dcl1
Gene Name Dicer like 1 
Synonyms (1) osDCL1
E.C. Numbers (0)
Pathway Reactions (0)
Gene Type Not sequenced
Has Phenotype yes
Description The Dicer-like protein is required for the generation and maturation of the miRNA (micro RNA) and siRNA (small interfereing RNA) type of ncRNA (non-coding RNA) molecules. These ncRNAs are involved in developmental regulation, genome maintenance and defense responses in the plants. Dicer protein belongs to the RNase III family of proteins. It cleaves the miRNA and siRNA precursors into the double-stranded duplexes. The duplexes are then unwound and the one strand is subsequently assembled into the miRISC or siRISC respectively. RICS is the RNA-induced silencing complex. The regenerated transgenic plants with DCL1 RNAi constructs display developmental abnormalities. The Strong loss of DCL1 function resulted in severe dwarfism, dark green color, rolled leaves and twisted shoots. Also observed were abnormal to complete arrest of root development. In plants with weak loss of fucntion, the narrow and outward folded leaf rolling, fewer adventitious roots, dark green color of leaves, dwarfism and ectopically developed chloroplasts were found in the adventitious roots. The miRNA accumulation in the leaves was either greatly reduced or absent. The DCL1 is a homolog of Arabidopsis DCL1 (AT1G01040) gene.
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toggle section Associated Ontologies (13)
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