Species | Oryza sativa (Rice) [ GR_tax:013681 ] | ||
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Accession | GR:0100120 | ||
Gene Symbol | Pair2 | ||
Gene Name | Homologous pairing aberration in rice meiosis 2 | ||
Synonyms (2) |
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E.C. Numbers (0) | |||
Pathway Reactions (0) | |||
Chromosome No. | 9 | ||
Gene Type | CDS (Protein coding) | ||
Has Phenotype | yes | ||
Description | The gene is essential for homologous chromosome synapsis at meiosis I. It encodes a HORMA-domain protein and is an ortholog of Saccharomyces cerevisiae HOP1 (YIL072W) and Arabidopsis ASYNAPTIC 1 (ASY1, At1g67370). The PAIR2 protein associates with axial elements at leptotene and zygotene stages of Meiosis and is removed from the AEs of arm regions when homologous chromosomes have synapsed. It promotes homologous chromosome synapsis. | ||
Curator Comment | Studies on histone H3 variant suggest that PAIR2 remains at centromeres until diakinesis, by this time the homologous centromeres are already synapsed. No precocious segregation of either the sister chromatids or kinetochore dysfunction were observed. In the pair2-null mutant, homologous chromosome synapsis is completely eliminated. PAIR2 does not play a role in AE formation, sister chromatid cohesion at centromeres or kinetochore assembly in meiosis I. |
Protein |
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Nucleotide (DNA) |
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Map Type | Map Set | Name | Map | Position | Ext. Links | |||
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Sequence | Gramene Annotated Nipponbare Sequence 2009 | BNL6.32 | Chr. 9 | 19,620,213-19,628,287bp | View Comparative Map | |||
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Map Type | Map Set | Name | Map | Position | Ext. Links | |||
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Genetic | JRGP RFLP 2000 | BNL6.32 | 9 | 75.4-78.1cM | View Comparative Map | |||
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Map Position [ View in Marker DB ] | |||||
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# | Map Set Name | Linkage Group | Start Position | Stop Position | CMap Feature Acc |
1 | JRGP RFLP 2000 | 9 | 75.4 cM | 78.1 cM | jrgp-2000-9-ip18 |
2 | Rice japonica MSU6 | Chr. 9 | 19620213 bp | 19628287 bp | grjp2009a-9-GR:0100120 |
Trait | meiotic cell cycle trait (TO:0000729) |
Plant Structure | megasporocyte (PO:0000431), microsporocyte (PO:0020047) |
Plant Growth and Development Stage | SE.00 stem elongation begins stage (PO:0007079) |
Cereal Plant Growth Stage | 4.1-panicle initiation stage (GRO:0007147) |
Cellular Component | nuclear chromosome (GO:0000228), nucleus (GO:0005634) |
Biological Process | leptotene (GO:0000237), zygotene (GO:0000238), synapsis (GO:0007129), megasporogenesis (GO:0009554), microsporogenesis (GO:0009556) |
Environment | unknown environment (EO:0007403) |
Chr | Start | Stop | Exp | Num. SNP Positions | |
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chr9 | 19,620,213 | 19,628,287 | ~160K SNPs x 20 accessions (McNally 2... | 0 | |
chr9 | 19,620,213 | 19,628,287 | '1536 chip' - 1311 SNPs x 395 rice ac... | 0 | |
chr9 | 19,620,213 | 19,628,287 | Huang X, et al, Nat Genetics 2010 Nov... | 18 | Search for SNPs |
chr9 | 19,620,213 | 19,628,287 | RiceDiversity 44K SNP assay, 34 trait... | 18 | Search for SNPs |
chr9 | 19,620,213 | 19,628,287 | RiceDiversity 44K SNP assay, 34 trait... | 0 |