Species | Oryza sativa (Rice) [ GR_tax:013681 ] | ||||||||
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Accession | GR:0080042 | ||||||||
Gene Symbol | MEL1 | ||||||||
Gene Name | MEL1 | ||||||||
Synonyms (7) |
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E.C. Numbers (0) | |||||||||
Pathway Reactions (0) | |||||||||
Chromosome No. | 3 | ||||||||
Gene Type | CDS (Protein coding) | ||||||||
Has Phenotype | yes | ||||||||
Description | Rice AGO gene MEIOSIS ARRESTED AT LEPTOTENE1 (MEL1) was identified from the analysis of seed-sterile mutants. In the mel1 mutant, chromosome condensation was arrested at early meiotic stages and irregularly sized, multinucleated, and vacuolated pollen mother cells (PMCs) frequently appeared in developing anthers. In addition, histone H3 lysine-9 dimethylation of pericentromeres was rarely reduced and modification of the nucleolar-organizing region was altered in mel1 mutant PMCs. The mutation also affected female germ cell development. These results indicate that the germ cell–specific rice MEL1 gene regulates the cell division of premeiotic germ cells, the proper modification of meiotic chromosomes, and the faithful progression of meiosis, probably via small RNA–mediated gene silencing, but not the initiation and establishment of germ cells themselves. |
Protein |
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Nucleotide (DNA) |
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Map Type | Map Set | Name | Map | Position | Ext. Links | |||
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Sequence | Gramene Annotated Nipponbare Sequence 2009 | BNL6.32 | Chr. 3 | 33,364,211-33,373,173bp | View Comparative Map | |||
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Map Position [ View in Marker DB ] | |||||
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# | Map Set Name | Linkage Group | Start Position | Stop Position | CMap Feature Acc |
1 | Rice japonica MSU6 | Chr. 3 | 33364211 bp | 33373173 bp | grjp2009a-3-GR:0080042 |
Trait | pollen sterility (TO:0000053), female sterility (TO:0000358), spikelet sterility (TO:0000436), male sterility (TO:0000437) |
Plant Structure | ovule primordium (PO:0000018), male archesporial cell (PO:0006014), female archesporial cell (PO:0006015), PO:0006442 (PO:0006442), PO:0006444 (PO:0006444), PO:0006463 (PO:0006463), inflorescence (PO:0009049), microsporocyte (PO:0020047) |
Plant Growth and Development Stage | D pollen mother cell meiosis stage (PO:0001009), sporophyte reproductive stage (PO:0007130), B meiosis of megaspore mother cell stage (PO:0007624) |
Cereal Plant Growth Stage | panicle development (GRO:0007157) |
Cellular Component | nucleolus (GO:0005730), nucleolus organizer region (GO:0005731), cytoplasm (GO:0005737) |
Molecular Function | siRNA binding (GO:0035197) |
Biological Process | male meiosis (GO:0007140), female meiosis (GO:0007143), megagametogenesis (GO:0009561), histone H3-K9 demethylation (GO:0033169), microgametogenesis (GO:0055046) |
Environment | abscisic acid regimen (EO:0007105), tissue culture growth media (EO:0007266), unknown environment (EO:0007403) |
Chr | Start | Stop | Exp | Num. SNP Positions | |
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chr3 | 33,364,211 | 33,373,173 | ~160K SNPs x 20 accessions (McNally 2... | 7 | Search for SNPs |
chr3 | 33,364,211 | 33,373,173 | '1536 chip' - 1311 SNPs x 395 rice ac... | 0 | |
chr3 | 33,364,211 | 33,373,173 | Huang X, et al, Nat Genetics 2010 Nov... | 20 | Search for SNPs |
chr3 | 33,364,211 | 33,373,173 | RiceDiversity 44K SNP assay, 34 trait... | 20 | Search for SNPs |
chr3 | 33,364,211 | 33,373,173 | RiceDiversity 44K SNP assay, 34 trait... | 2 | Search for SNPs |